Endocrine Abstracts

The loss of regulatory control of the cell, leading to unrestrained cell proliferation, is a hallmark of cancer. In a number of cancers, over expression of cyclin A and cyclin B1 proteins has been reported and in some instances the level of expression correlated well with the grades of malignancy. In the present study, we analyzed, by immunohistochemistry, the expression of cyclins A and B1, proteins enable passing G(2)-restriction point, in different histological variants of ...

The introduction of the new classification of the thyroid FNAB results which stratifies the risk of malignancy of thyroid follicular lesions is of special interest in endemic and postendemic areas. In such regions patients with non-neoplastic nodular goitre predominate and nodules diagnosed previously as ‘follicular neoplasm’ showed to be thyroid cancer less frequently than in iodine-rich areas.The aim of the study was to evaluate the frequency...